Sentence examples for large problem in the from inspiring English sources

Joseph Ciolino, an ophthalmologist at the Massachusetts Eye and Ear Infirmary and Harvard Medical School, says the need for such a device is great: "Cataracts are the leading cause of blindness worldwide and a large problem in the developing world.

However, the VIFs for our models are low, with an average VIF being around 2. As such, multicollinearity is not a large problem in the models.

Low back pain (LBP) is a large problem in the Western world.

A large problem in the current pharmaceutical industry in China is the over-capacity of active pharmaceutical ingredients and chemical drugs without high technical innovation [ 29].

One potentially large problem in the field of ROS may be the use of in vitro models to observe cytoprotective effects of antioxidants.

Different expression levels in group III and group V were not detectable after 10 days (p > 0,05) Peritoneal carcinomatosis represents a large problem in the treatment of colorectal carcinomas.

"We've seen an attack on innocent people in order to stimulate the ethno-sectarian violence that was really a large problem in this country in the last couple of years," the chief American military spokesman, Brig.

With many large problems in the world, even the wealthiest philanthropists need to work with others.

Deutsche Bank - Germany's largest lender - has faced some large problems in the past 12 months.

This poses large problems in the correct assembly of large multi-gene family genes such as var genes.

Also, high regression coefficients and high correlations between the predictors may cause large problems in the estimation process, resulting in very low power even with EVP of 20 or more [ 67].