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In contrast, NF-κB 1 and 2 proteins are synthesized as large precursors, p105 and p100, which generate the mature p50 and p52 subunits, respectively.
The large precursors encoding plant miRNAs have the potential to encode multiple miRNAs, either identical or different.
Additionally, p50 and p52 members are synthesized by proteolysis of their large precursors, named p105 and p100, respectively.
Under both conditions, Rpm1r is not properly processed to its mature form, and large precursors of mtRNase P RNA accumulate [59,69].
These short molecules (20 25 nucleotides long) are processed from large precursors (pri-miRNAs and pre-miRNAs) and transported to the cytoplasm.
Using a bioinformatics search to look for typical enzymatic cleavage sites in other large precursors of peptide hormones, Zhang et al. identified a 23 amino acid region of pre-proghrelin that is flanked by potential convertase cleavage sites.
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A large precursor supply promotes GA biosynthesis.
The AaSP1 gene encodes a full-length protein of 515 amino acids as a large precursor of 56 kDa.
For example, antibody studies showed that it is located in the Golgi apparatus and endosomes, two structures within cells in which b-amyloid is known to be cleaved from its large precursor protein.
The genome of EV71 consists of a positive sense, single-stranded RNA of ∼ 7400 bp, encoding a large precursor polyprotein that requires proteolytic processing to generate mature viral proteins.
The eruption was preceded by a large precursor earthquake three days before.
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