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The AaSP1 gene encodes a full-length protein of 515 amino acids as a large precursor of 56 kDa.
The biogenesis of ribosomes is initiated in the nucleolus by the transcription of a common large precursor of mature ribosomal RNAs.
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Under both conditions, Rpm1r is not properly processed to its mature form, and large precursors of mtRNase P RNA accumulate [59,69].
Using a bioinformatics search to look for typical enzymatic cleavage sites in other large precursors of peptide hormones, Zhang et al. identified a 23 amino acid region of pre-proghrelin that is flanked by potential convertase cleavage sites.
In most insect species vitellogenins are synthesized extraovarially in female fat body cells as large precursor proteins of vitellin (the major yolk protein of insects).
Large precursor molecules of NF-kB (p105 and p100) are processed by the ubiquitin/proteasome pathway which involves the degradation of ankyrin repeat c-terminal regions.
It is synthetized by granular keratinocytes as a large precursor consisting of 23 homologous repeats and a S100-homologous N-terminal domain.
MiRNAs originate from the maturation of larger precursors of approximately 70 nt called pre-miRNAs.
Baz plays a major role in the assembly of E-cadherin puncta into larger precursors of AJs (McGill et al., 2009).
The large precursor pool sizes of early binders in the ΔrimP strain are further confirmation of a delay in assembly.
TGFβ1 is synthesized as a large precursor molecule consisting of an N-terminal prodomain (LAP) and a C-terminal mature domain.
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