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We have shown here that conventional methods used for decellularizing thin tissues can also be applied to large organs, such as IVD.
The maximum and mean doses to large organs such as the PTV, brain stem, and parotid gland for the TPS, SR and sandwich MC simulations did not show any significant difference; however, significant dose differences were observed for very small structures like the right 8th cranial nerve, right cochlea, right malleus and right semicircular canal.
Large organs such as the one installed in 1361 in Halberstadt, Germany, the first documented permanent organ installation, likely prompted Guillaume de Machaut to describe the organ as "the king of instruments", a characterization still frequently applied.
Optical imaging has been used to probe surface structures, such as the functional activation of the exposed brain regions [ 1], skin cancers [ 2, 3], and those revealed by endoscopic procedures [ 3, 4], but it has also been used to investigate noninvasively the internal function of large organs such as the breast [ 5, 6, 7] and the unexposed brain [ 8, 9].
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Arabidopsis plants expressing OsARGOS led to larger organs, such as leaves and siliques, compared with wild-type plants.
The binding proteins serve as reservoirs of the two hormones to protect the tissues from sudden surges of thyroid hormone production and probably also to facilitate delivery of the hormones to the cells of large, solid organs such as the liver.
However, regeneration of large inner organs, such as lung, remains one of the biggest challenges to modern medicine.
Three-dimensional (3D) photofabrication is expected to be fully utilized for microfabrication of 3D scaffolds for engineering large human organs such as the liver.
One potential cause of variation in BMR (or resting metabolic rate, RMR) is that some individuals obtain a large amount of energy regularly and therefore have large metabolically-active organs, such as a large gastro-intestinal tract, heart or skeletal muscles (Hammond and Diamond, 1997; Speakman et al., 2003).
The time activity curves in rats (Figure 5) show that large blood pool organs such as the liver, spleen, and kidneys had a lower tracer uptake and retention compared with the heart (SUV of 2.5).
Scientific America reported how the flight-or-fight response to extreme fear releases chemical toxins, which in large amounts can damage organs "such as the heart, lungs, liver and kidneys".
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