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It has been speculated that miRNAs have a role as a dosage regulator, through expression-level repression following large or local genome duplication events [ 40].

Overall, our data may suggest miRNAs as a dosage regulator playing a possible role in R-genes functional redundancy erosion following large or local duplication events.

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However, May no longer invests money on behalf of pension funds of large corporations or local authorities, instead filling the role of go-between.

Thomas Jefferson, the only true gourmet among our presidents, waxed ecstatic over fresh vegetables and kept a chart of when certain ones were available in his own large garden or local market.

Despite the dazzling visual feast and Hockney's enthusiastic pursuit, there is actually no point in "Secret Knowledge" where an appeal to optical aids, to explain either large developments or local oddities, seems both necessary and persuasive.

Such information may be obtained from unearthed stone stelae, notes kept by individuals, genealogy of a large family, or local orally spread legends.

As of 2017, almost every large employer or local institution that Tilbury could traditionally claim as its own has been privatized, shut down or both.

Thus, the mutations do not induce large global or local conformational changes.

However, when the number of local models that form the polytope is large or the local models are too different, the performance of the algorithm deteriorates.

C. SPEED Independence, Calif., Oct. 31, 2012 To the Editor: Re "A Big Storm Requires Big Government" (editorial, Oct. 30): A big storm (or any big emergency) doesn't ipso facto require big government; it requires capable, efficient government — large or small, local or national.

For instance, Rabinowitz [ 3] and Rabinowitz et al. [ 4] suggested categorizing plant species according to geographic range (large or small), local population size (large or small) and habitat specificity (wide or narrow).

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