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However, in most cases the large number of uncertain parameters leads to an underdetermined and ill-posed problem.
Given the large number of uncertain factors in any biological experiment, probabilistic methods are natural in this setting.
The associated reliability problems are characterized by means of a large number of uncertain parameters (hundreds or thousands).
This paper draws attention to a fundamental problem that occurs in applying importance sampling to 'high-dimensional' reliability problems, i.e., those with a large number of uncertain parameters.
These methods are merged into the strategy for process flow sheet optimization with a large number of uncertain parameters,which is illustrated with bioethanol case study.
This work presents a solution strategy for design and synthesis of flexible process flow sheets with a large number of uncertain parameters, i.e. 50-100.
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This paper presents a robust computational methodology for the synthesis and design of flexible HEN (Heat Exchanger Networks) having large numbers of uncertain parameters.
Among body sites, inferences at the anterior nares and posterior fornix sampling distributions were the most unreliable, owing to the relatively limited number of samples at these sites (Extended Data Fig. 4a), reflected as a large number of highly uncertain features at these sites (Fig. 3).
In addition, there are a large number of variants of uncertain significance (VUS).
Mathematical models of signal transduction pathways are characterized by a large number of proteins and uncertain parameters.
Complex systems such as spacecraft have large number of fuzzy and uncertain factors with the nonlinearity degree increasing with technological development; in other words, integrated system health management (ISHM) has become an increasingly important application complex problem and has received a great deal of attention by governments and researchers.
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