From this perspective, the large number of targets may not be advantageous when developing miRNA-targeted strategies.
Military planners already have coordinates for a large number of targets across Afghanistan and in the capital, Kabul.
On a surprisingly large number of targets used as development indicators, the US fares poorly – in some cases, even worse than developing countries.
This concept can potentially be expanded to a large number of targets and to in vivo applications.
Recent developments toward molecular imaging of a large number of targets have introduced the use of multiple rounds of labelling and imaging3,4.
The requirement of laboratory with large number of targets to perform existing TLS calibration procedures make them unfeasible for most TLS users.
The sequential Monte Carlo (SMC) implementation of the probability hypothesis density (PHD) filter suffers from low computational efficiency since a large number of particles are often required, especially when there are a large number of targets and dense clutter.
The analysis of the expected yields of a representative set of those surveys both from ground and space shows that they will be able to provide a large number of targets, covering an ample range of planetary and stellar parameters, fitting the EChO capabilities.
Since these decoy sets include a large number of targets satisfying the aforementioned condition of chemical equivalence, we use these sets to assess how BACH's performance is affected by the presence of bound partners (e.g. ligands or other protein chains) in the native conformation.
While a range of radioligands are available for the central nervous system (CNS), a large number of targets do not have a suitable radioligand.
This 'Big Data' set covers large number of targets reported in the literature and can be used for building holistic multi-target QSAR models for target prediction.
