The phrase 'large number of problems' is correct and can be used in written English.
You can use it when referring to a significant amount of issues or difficulties. For example: The public health system in the city is facing a large number of problems, including overcrowding and outdated equipment.
This property finds use in a large number of problems.
"There remains a large number of problems in Odessa: preserving sovereignty, territorial integrity, independence and peace," Poroshenko said.
A 79-page report by the CQC has revealed a large number of problems at the trust.
Earlier studies have already registered a large number of problems regarding railway noise.
Numerical methods are used within the field of power engineering to solve a large number of problems.
Over the years, computer vision researchers have developed a number of algorithms to solve a large number of problems.
So understanding when you need a small or a large number of problem solvers is crucial.
The big advantage of an open network is its potential to attract an extremely large number of problem solvers and, consequently, a vast number of ideas.
The repurchases are important to taxpayers, because — through Fannie, Freddie and the Fed — the government now owns or backs a large number of problem loans and related securities.
The agency has said its examiners found that Silverado managers were deficient in assessing the creditworthiness of borrowers, concentrated too much of the institution's business in commercial loans amid a depressed market and conducted an exceptionally large number of problem transactions with insiders, including shareholders, officers and directors.
This paper describes software called computer assisted reduced mechanism problem solving environment (CARM-PSE) that gives the engineer the ability to rapidly set up, run and examine large numbers of problems comparing detailed and reduced (approximate) chemistry.
