Sentence examples for large number of modification from inspiring English sources

It is likely that this relates to mRNA-independent post-translational modification, trafficking, and degradation, as a large number of modification sites and domains exist in GOT1.

It is true that the fiscal compensation mechanisms for the tax which were proposed to the road haulage industry were at the very least open to criticism on the grounds of their complexity and the large number of modifications they underwent.

The advantages associated with the unique structure of albumin imparts it with the ability to interact with variety of molecules, while the functional groups present on their surface provide base for large number of modifications making it as an ideal nanocarrier system.

The initial conditions were based upon those described by Lo Surdo and coworkers with a large number of modifications [8].

A large number of modifications, including ectopic expression of the mevalonate pathway and the A. annua genes for ADS and CYP71AV1 resulted in production of artemisinic acid.

The discovery of a large number of modifications is of great significance for follow-up research and would aid in the early discovery of cancer markers [ 23].

A large number of modifications can exist depending on the specific context or DNA process, and positive and negative interactions between different modifications also occur (for review see Kouzarides 2007).

Because unproductive recombination events increase the amount of screening required to identify colonies with the desired mutation, the synonymous codon strategy significantly improves the efficiency of the procedure, which is of particular importance for endeavors requiring a large number of modifications.

Nevertheless this estimate represents a much larger number of modification types than can be considered by commonly used, but often restrictive PTCM search algorithms such as Sequest, X!Tandem, and Mascot [ 12- 14].

Top-down proteomic studies from the laboratories of Freitas and Kelleher have also provided extensive information concerning the complexity and large number of distinct modification patterns that can occur on histones, but these methods do not address the substrate specificities inherent to individual enzymes and do not explicitly define the stepwise progression that connects two states (53, 54).

In addition, a large number of design modifications have been considered.