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I'm sure there are dozens of very large niches of content types that are particular to parts of the world that have developed followings in other parts.
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More private areas for devotion were located at the building's outer wall, where large niches served as "chapels of the hearing ear" for individuals to speak to the god.
One study reported very low uterine incisions to be an independent risk factor for the development of large niches (Osser et al., 2010).
This thought is supported by two studies that indeed report a higher prevalence of large niches in women with retroflected uteri, although the uterine position before the CS was not registered in these studies (Osser et al., 2009; Bij de Vaate et al., 2014).
In patients with large niches, i.e. thin residual myometrium of less then 3 mm a hysteroscopic niche resection is expected to be at higher risk of bladder injury and uterine perforations.
During combined hysteroscopic and sonographic evaluations we became aware of the fact that large niches are often located in the (lower) uterus.
Vaginal discharge of brown mucus is a frequent symptom in women with large niches.
(Large niches, granted, but niches nonetheless).
Habitat fragmentation negatively affected epiphytic and epiphyllous bryophytes and increased the representation of species with larger niches (generalists) while decreasing the representation of species with smaller niches (typically found in shady or in sunny areas).
One of the largest niches in the CNS harbouring these cells is the SVZ (subventricular zone), although other regions within the brain contain NPCs as well, such as the spinal cord subependymal zone, the hippocampus dentate gyrus subgranular zone and the previously described sub-cortical zone (Merkle and Alvarez-Buylla, 2006; Kriegstein and Alvarez-Buylla, 2009; Miller and Gauthier-Fisher, 2009).
An interesting observation is that a lot of our patients seen for laparoscopic niche repair of large symptomatic niches have retroflected uteri.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com