Sentence examples for large mutation from inspiring English sources

Secondly, the LARGE mutation present in the Large myd mouse model of muscular dystrophy results in defective α-DG glycosylation (Grewal et al. 2001).

Not having mutations with high scores does not preclude a gene being a potential driver gene, but these cases tend to be infrequently mutated genes that occur in samples with large mutation rates as was the case for CDH11 and PDGFRA.

We discuss deviations for large mutation rates and including back mutations.

The rationale is that a large mutation rate would make the GA search to resemble a random search.

For very large mutation rates, the optimum fitness landscape is flat and has a single peak at type B.

The only large mutation characterized is the 2.5 kb deletion of exon 55 in the Ashkenazi Jewish population.

Large mutations, which include alterations to chromosome structure and number, are relatively rare because most cause such major disruptions to development that the fetus is naturally aborted.

Recently, new large mutations have been identified in the nebulin gene (NEB) causing nemaline myopathy (NM).

(3) In Fig. 2c, the H value curve of the elastic strip area is not stable and has large mutations.

But the gradualists felt that large mutations were nearly always deleterious while selectively advantageous mutations would be too rare to be important.

Here, we report the genome sequence of LS5218 and a list of large mutations and single nucleotide permutations (SNPs) relative to E. coli K-12 strain MG1655.