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By this definition the number of local maxima automatically yields the number of modules, and at the same time all small and large modules are identified simultaneously.
Second, the passenger genes of large modules are enriched with the putative targets of their regulators or drivers.
As shown in Figure 2, the two large modules are dominated by neuro-related signal transduction and immune related pathways, respectively.
We find that large modules are less factorizable than small modules: there is a strong negative correlation between module factorizability F(A) and module size.
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One factory module can turn 40,000 pounds of plastic into 130 barrels of oil a day, and larger modules are on the way, according to Bob Schwarz, Agilyx's chief financial officer.
The largest modules are strongly implicated in post-translational protein modifications and signal transduction processes (e.g., Modules 5, 10 and 16).
The neutronic performance of the core relative to a single reflected module and a very large module is investigated and the use of modules is found to be a good choice.
Cells with the active area of 0.94 cm2 (smaller modules) and 1.36 cm2 (larger modules) were monolithically connected together by overlapping eight cells in series.
With increase in the overall clustering proportion confluence of individual clusters to larger modules is observed and, finally, large-scale aggregates, such as the tonotopic organization, are seen for maps with high clustering proportion.
Five of the eight modules including the first and largest module was strongly associated with tumor grade.
Pathways associated with the largest coexpression modules are shown in the legend of Figure 4A.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com