Sentence examples for large modifications of from inspiring English sources

The other consists of the changes brought about by mutations, spontaneous alterations of genes that result in large modifications of the organism and give rise to new species: "The new species thus originates suddenly, it is produced by the existing one without any visible preparation and without transition".

Both multiple mutants display large modifications of stability and activity arising from synergic effects in comparison with single mutations.

The methods in [7, 8, 9, 10, 11, 12, 13, 14] need large modifications of the radomes or antennas and lead to high cost.

The notion of hypersensitivity is illustrated: a weak geometrical modification, a defect in connexion angle, can under certain conditions lead to large modifications of the vibrational behaviour.

Cold acclimation is associated with large modifications of gene expression [ 3- 6].

Adaptations to a new environment, such as a polluted one, often involve large modifications of the existing phenotypes.

From the results for the given numerical example, it is shown that even in the cases with a large modification of structural parameters the proposed iterative procedure can provide exact predictions of the modified modal parameters after only a few iterations, and the high order approximation approach can give excellent estimates.

Consistently the proteomic analysis shed light on large modification of enzymes involved in the transport and catabolism of metabolites necessary for energy production.

This was well demonstrated by the model, where the large CaMK facilitation could be expected to produce a large modification of E-C coupling, but in silico the effect turned out to be rather small.

Native LARGE modification of α-DG is regulated directly and/or indirectly by the activities of a number of other enzymes, including HNK-1ST, B3GNT1, and possibly SLC35A1 and POMGNT1 (see below).

Overexpression of LARGE has been shown to lead to LARGE modification of non-native acceptors, including N-glycans and O-GalNAc glycans, and, potentially as a consequence, to partially rescue functional glycosylation in cells derived from patients deficient in other O-mannosylation pathway activities.