Sentence examples for large modifications in from inspiring English sources

Despite large modifications in the membrane composition, the local environment of core complexes remained unaltered, whereas specialized paracrystalline light-harvesting antenna domains grew under low-light conditions.

Calcium-related effects can be readily ruled out in reduced [Cl−]o experiments: 1) changes in subunit composition (differentially calcium-permeable) are unlikely here, 2) isethionate can bind calcium ions, but benzenesulphonate does not; 3) large modifications in [Ca2+]o have negligible effects on the EACh.

Neither did we observe large modifications in the expression of genes coding for surface receptors; such changes are occurring later in human ESC differentiation into embryoid bodies [ 52].

Pga31 mutant strain shows pleiotropic phenotypes with large modifications in cell wall composition and caspofungin sensitivity, suggesting a function in the early steps of cell wall biosynthesis or in cell wall salvage pathways.

As a consequence, large modifications in single fluxes are prevented in MOMA; however, such large modifications may be required for rerouting metabolic flux through alternative pathways [ 22], which has been observed in experiments [ 23].

First, 5-flurouracil pharmacokinetics is non-linear due to saturable liver metabolism corresponding to DPD enzyme, such that even a small change in dose could be associated with large modifications in AUC.

Subsonic shell waves are demonstrated to interact strongly with supersonic shell waves to cause a large modification in the radiated intensity distributions near the shell surface.

However, as previous results have shown that the use of Ca-salts of flaxseed oil did not allow a large modification in milk fat composition, the cheapest flaxseed product will be recommended to incorporate in the dairy cow diet.

Carbonate production stayed active through the Ladinian magmatic phase, but the onset of volcanism was associated with a large modification in the platform carbonate facies, which became dominated by automicrites.

Although structural changes in [Mn6]2+ as a cause of the large modification in the relaxation dynamics certainly cannot be ruled out, it seems likely that the role of the [ReIVCl6]2− anion is non-innocent.

After evaluating possible gene structure changes brought by each SNP in FJ81278 and HN19311, it was found that 104 genes contained SNPs located in start, stop codon or splice sites which causing large modification in protein sequences and thus altering their functions indel(Additional file 3: Table S1).