Sentence examples for large linkage groups from inspiring English sources
The two-point analysis resulted in 18 large linkage groups (LOD > 75) each assigned to one of the porcine chromosomes using the comparative map from INRA [ 19].
Only five markers were omitted as causing problems with the fit, and JoinMap's mean chi-squared criterion for the resulting maps was below 2.5 for each of the eight large linkage groups.
A total of 438 markers were assigned to 11 large linkage groups and some small or non-integrated linkage groups; the total observed map length was 1372.2 cM, and the average marker interval was 3.0 cM.
A total of 3329 of the markers could be assigned into 18 large linkage groups, while the remaining 1504 markers which could not be linked to any of the large groups were discarded.
The YI pedigree used to determine the positions of the outlier loci of C. japonica has previously been used to construct a linkage map in which a total of 1261 markers were assigned to 11 large linkage groups, giving a total map length of 1405.2 cM (Tani et al. 2003, Moriguchi et al. 2012).
There is one large linkage group of 288.5 cM, which is approximately one third larger than the largest linkage group in the D. pulex linkage map.
The latter revealed an abnormally large linkage group covering close to half of the map.
It is apparent that some large gaps remain in the RFLP genetic map by Jan et al. (1998), which split a large linkage group into small ones, such as LG17, 18, 19 and 20.
Two markers failed to produce satisfactory results, 7 markers corresponding to two regions of HSA1 mapped to the GGA21 linkage group, 3 markers to GGA23, 4 markers showed no linkage to a known chromosome or to a large linkage group and, finally, 13 markers were grouped into a new linkage group, together with 13 other markers from the ChickRH server database.
To validate the map ordering of CRI-MAP, markers belonging to a large linkage group with a range of informative loci (LG8 - established by AUTOGROUP in CRI-MAP) were chosen to build an independent sex-average comprehensive linkage map with CarthaGène version 1.0 which incorporates an EM (expectation-maximization) algorithm and a local search technique to build a maximum likelihood map [ 26].
All the 13 markers of the new large linkage group, including the one from E26C13, were developed from chicken supercontigs with sequence similarity to the region 147.7 to 158 Mb on HSA1 in the Hg17 assembly and are now in the region 148 to 158 Mb in Hg18.
