"large knowledge gaps" is a correct and usable phrase in written English.
You can use it to describe a situation where a lot of information is missing or unknown. For example, "Our research has identified large knowledge gaps in the field of renewable energy."
Currently, there are large knowledge gaps for fundamental properties needed to build models that can provide such predictions.
The Green Violetear is a common and widespread species, yet there are large knowledge gaps on much of its life history.
There are large knowledge gaps in this area of research and consequently only very crude empirical criteria are used in the industry.
However, because of the complexity of DOM and the shortage of useful characterization methods, large knowledge gaps exist in our understanding of the interactions between DOM and ENPs.
In order to design safe and efficient infrastructure for CCS, the exact properties of these mixtures are required, and currently there are large knowledge gaps that need to be closed regarding the phase behavior.
Large knowledge gaps still exist on the toxicological mechanisms of silver (Ag) engineered nanoparticles (ENPs); a comprehensive understanding of the sources, biodistribution, toxicity and transformation of Ag ENPs along their life cycle and after transfer in living organisms is needed.
There is however still a large knowledge gap concerning effects of P on methane oxidation.
The large knowledge gap also results in difficulties predicting the consequences of anthropogenic activities and predicting recovery timelines12.
Internship outline: I had two goals prior to applying for summer research funding: 1) to garner malaria entomological skills from rural fieldwork and laboratory settings, and 2) to study Anopheles where large knowledge gap in malaria vector still exists.
Despite this very high number of people who are suffering, there is a large knowledge gap regarding the mechanisms by which neurological recovery occurs, and not a single FDA-approved therapy available to help people recover.
We believe that there is a large knowledge gap in the area of women's health in developing countries, and there is an urgent need to conduct appropriately designed studies.
