The gut, or gastrointestinal tract -- the long tube that starts at your mouth and ends at your, well, you know -- is your largest interface with the environment, spanning the width of two football fields if unrolled and laid flat.
Since the gut is the largest interface with external microbes, and frailty is associated with chronic inflammation [ 11], it is likely that the gut microbiome has a role in frailty.
Extremely large interface area with asphalt binder matrix is the most important feature of these nanoparticles which translates in a higher degree of changes in the microstructure of asphalt binder.
One of them (rs2722722: H484Y) is probably in contact with DNA, as an equivalent residue in a homologous structure shares a large interface area with DNA (1MEY:C19; area = 47.1 Å) as shown in Figure 4A.
In StPurL, the FGAM synthetase domain forms larger interfaces with the glutaminase and the N-terminal domains, burying 4,700 Å and 1,900 Å, respectively, compared to 2,800 Å and 1,400 Å for TmPurLQS.
Demkowicz, M., Hoagland, R., Uberuaga, B. & Misra, A. Influence of interface sink strength on the reduction of radiation-induced defect concentrations and fluxes in materials with large interface area per unit volume.
Besides, an interpenetrated heterojunction of NTs:QDs with large interface area facilitates electron transfer from CdTe NTs to the closely surrounding CdSe QDs, and electron transport also benefits from the dense and ordered assembly of QDs in the network.
As seen in Figure 7a, dense and ordered assembly of CdSe QDs is readily formed in the network of branched CdTe, which enables a close heterojunction contact with a large interface area.
The CC dimer (Fig. 1a) is organized around a two fold axis with a large interface involving, in particular, helices α1 and α5 (residues 172 184) [30], [30].
BcsA and BcsB form a stoichiometric complex, with a large interface.
