Sentence examples for large functional consequence from inspiring English sources

Intron retention, or the maintenance of an intron in a mature mRNA transcript, is a less common type of alternative splicing [ 12] and can have large functional consequence by introducing premature mutations to the mature transcript.

This can lead to large functional consequences on soil structure and thus on air and water fluxes in the soil.

A shift in DNA methylation of 5 10 % indicates that ~5 10%% of DNA molecules in the population assessed become fully methylated (or unmethylated) at that locus, with potentially large functional consequences in that specific cellular sub-population.

Interestingly, despite the huge difference in the expression profiles, these two actin genes only differ by four amino acids, indicating that small mutations between these two genes may have large functional consequences.

Enhanced light capture is a functional consequence of large eyes, but not necessarily the "explanation" for large eyes that Nilsson and colleagues argue they have provided.

As a functional consequence, a large proportion of these receptors are Ca2+ impermeable.

Although the functional consequence of this large gene size is not clear, one predicted outcome is an extended time period for transcription of the corresponding mRNA.

To gain insight into the functional consequence of androgen-action, A large-scale association analysis was performed comparing our androgen up-regulated protein data set of 126 proteins with each of the 13364 concepts in the MCM [23].

In addition, we conclude that complete loss of merlin or large truncations of merlin because of nonsense or frameshift mutations might have a functional consequence.

While the strong binding constant and large FRET value measured for cytosolic PLCβ1 and TRAX suggest a specific cellular role, the functional consequence of these proteins' association is not yet clear.

Thus, the functional consequence of Nef on MHC-I and CD4 expression is different.