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Also, detected patterns for the change, particularly in cortical area and volume, largely overlapped with those found in our analysis, showing large effects in middle temporal and frontal areas.
While these studies don't find large effects in the long run, we note that these long-run effects are harder to measure and are thus more uncertain.
Despite shortcomings in the evidence base, several studies show large effects in programmatic timeframes.
A polygenic cancer would show small effects in family studies but large effects in twin studies.
The significant change of the CSL and the critical state parameters (λcs, Γcs, and ϕ'cs) would have large effects in estimating soil state parameter.
Using this design, we found that eQTLs and sQTLs with large effects in the family were enriched with rare regulatory and splicing variants (minor allele frequency < 0.01).
Note that Cohen's d values indicate the magnitude of the two effects, where values of 0.2, 0.5, and 0.8 are considered to be small, moderate, and large effects in the psychological literature (Cohen, 1992).
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This strategy is robust in identifying highly penetrant variants, such as genes of large effect in Mendelian diseases.
A large effect in favor of controls was found for the time taken to complete the affective ToM task.
Bile salts had a large effect in stimulating lrp and gyrB expression (Fig. 3B).
Reverse phenotype strategies are becoming more feasible, given the accumulating evidence for the existence of genetic variants of large effect in a substantial proportion of the ASD population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com