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The BIG family members DDB_G0273101 and DDB_G0273831 are identical copies and are located in the large duplication of chromosome 2 which is only present in D. discoideum strains AX3 and AX4 [13].
One DMD patient presented with mental retardation associated with a large duplication of exons 65 79.
Here we present evidence of a large duplication of the mitochondrial genome in the evolutionary history of the Sulidae.
A large duplication of sequence between 7p14.3 and 7p15.1 was identified during the annotation of human Chromosome 7 [ 23].
Array-CGH analysis was conducted only for patient 4 and demonstrated a large duplication of near 34 Mb del 9p24.3-p13.3.
Evidence has been presented that genes in a large duplication of coding region in a scorpion fly (Order Mecoptera) were initially functional (Beckenbach 2011).
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A technique is described that uses a Tn10 derivative, Tn10dTc‐araC+, which contains a cloned copy of the Escherichia coli araC+ gene, as a portable region of homology to generate large duplications of the Salmonella chromosome.
The existence of CNVs whose frequencies are associated with environmental conditions, including large duplications of many genes, provides an excellent opportunity to study the influence of selection in the initial stages of gene duplication [31].
However, all genomes contain relatively large duplications of chromosome II.
The most common large duplication was duplication of exon 2 (11% of duplications).
The most commonly occurring large duplication was duplication of exon 2 in all three databases.
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