Sentence examples for large difficulties in from inspiring English sources

It is well known that AT richness and repeat structure of var genes poses large difficulties in the assembly of short sequence reads.

One of the largest difficulties in fatigue damage is to find a representative 'Damage indicator' which can be easily connected with the Wöhler curve taken as known data of the material.

It was concluded that Neolithic men and their ground flint axes had no great difficulties in making large clearings in the forest for the purposes of cultivation.

But there is a larger difficulty in America's reclaiming its former pre-eminence.

The largest difficulty in considering the Kerik downfall is knowing in which niche of public disgrace to categorize him.

LG maize cultivar has a larger potential to adapt changing climate, but has a larger difficulty in improving yield because of lower tolerance of high plant density.

The anatomical features of the male urethra are different from females in terms of length, stegnosis and arcuations; these differences may predispose male infants to urinary tract calculi because of the larger difficulty in passing stones.

However, although the amplification provided by hearing aids can improve speech understanding in quiet, persons with hearing impairment still have disproportionately large difficulties understanding speech in noise.

The development of anti-adhesion therapy targeted at the microbial lectins is hampered by the great difficulty in large-scale synthesis of the required inhibitory saccharides.

Above all, experts say, the difficulties in streamlining ERT are emblematic of the larger difficulties of changing anything in the Greek public sector, a vast web of overlapping and interconnected interest groups, each one dependent on the other for survival.

Yet reliable data depicting the nature and extent of changes in population parameters is sparse, primarily due to logistical problems in covering large areas and difficulties in obtaining reliable information at large spatial scales, particularly over time.