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Discover LudwigSuggestions(5)
"large differences" is correct and usable in written English.
It can be used anytime to indicate that two things are very distinct from each other. For example, "There are large differences between the two candidates' stances on education policy."
Exact(58)
The large differences in linker lengths suggest different docking modes.
Large differences of temperatures were obtained from different fringes.
These large differences in culture and background make us perceive many things differently.
But the large differences matter more.
There are large differences by race and ethnicity.
Large differences between the two groups look smaller.
Mr. Beschloss noted the large differences between Vietnam and the current military action.
The sources of such large differences make for a slightly complicated story.
Over all, the assessment reported large differences in quality between lines.
There are large differences in standards, and the system is complicated to navigate.
Money found that, although direct providers usually offer the best deals, there were still large differences.
More suggestions(15)
enormous differences
vast differences
numerous differences
overwhelming differences
significant differences
wide differences
sizable differences
formidable differences
appreciable differences
massive differences
mighty differences
strong differences
major differences
tremendous differences
considerable differences
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com