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The gene families involved in RNA silencing in plants have evolved to provide a large degree of functional diversity.
In all, Y-family polymerases in eukaryotes display a large degree of functional divergence, rendering them highly specialized for specific roles in lesion bypass [4].
In fact, there is a large degree of functional redundancy between RARs which have important roles in many distinct stages of embryonic patterning and organogenesis [ 3].
Importantly, the human Y-family enzymes demonstrate a large degree of functional divergence due to the fact that during TLS, the nucleotide incorporation fidelity and efficiency of each Y-family polymerase is lesion specific.
In addition to their differential regulation, the various HSPs also show a large degree of functional diversity with respect to client specificity and client processing (Kampinga and Craig, 2010).
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First, it must be noted that a large degree of non-functional overlap can be expected, because of the widespread distribution of the biochemical events.
Since such proteins are at the intersection of numerous pathways, a large degree of interaction allows the virus to reach into many different functional processes.
Although the aim of this review was to assess the predictive and prognostic utility and the additional benefit of functional imaging on target volume definition in oesophageal and pancreatic cancer, the lack of heterogeneity in the functional imaging modalities used and the large degree of variation in technique and reporting make comparison of the results challenging.
Functional enrichment analysis of the biological conditions also indicated a large degree of overlap in the host response – at least qualitatively – irrespective of the virus used to infect the mice.
This suggests a large degree of uncertainty.
"Hands have a large degree of freedom," Nojavanasghari added.
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