Sentence examples for large conformational changes from inspiring English sources

Binding of diacylglycerol to the C1 domain and calcium to the EF domain would induce large conformational changes that are incompatible with the closed, autoinhibited conformation.

Necessarily, the proteasome undergoes large conformational changes during its operation.

PKG is homodimeric and large conformational changes accompany cGMP binding.

In contrast, large conformational changes occur during heat activation (Yang et al., 2010).

F protein refolding involves large conformational changes of the protein trimer.

Biomolecular recognition often involves large conformational changes, sometimes even local unfolding.

Large conformational changes are observed when the ligand-free protein is bound to WAMP.

Here, we describe the "confine-convert-release" (CCR) method, which is applicable to large conformational changes.

Biomolecular associations often accompanied by large conformational changes, sometimes folding and unfolding.

During the process of uncoating, the viral capsid undergoes large conformational changes, which can be monitored by sedimentation velocity experiments.

The observed inter-domain structural plasticity of Pelota proteins suggests that large conformational changes are essential for their functions.