Sentence examples for large changes over from inspiring English sources

In his new book, "Time Travel," James Gleick argues that before the invention of the printing press, less than six hundred years ago, notions of any sort of temporal dislocation were next to impossible; people saw the future as relatively similar to the past — large changes over time simply weren't visible or accessible.

Large changes over time in the tumour size and the underlying biochemistry will therefore definitely affect heterogeneity.

The authors looked not only at the current trends in self-citation but also at how they evolved over time, finding large changes over the past decades.

Positive cooperativity makes enzymes much more sensitive to [S] and their activities can show large changes over a narrow range of substrate concentration.

However, the statistical distribution of TCR clonotypes incurs large changes over time according to the personal history of antigen encounter.

Such fluctuations can incur strong selection, but the responses of the population will not add up to large changes over longer timescales (Gingerich 1983; Gibbs and Grant 2006).

In addition, our analysis evaluated intakes in 1990 and 2010, which does not exclude larger changes over a broader time horizon.

Even under larger changes over evolutionary time, the tendency of the system to stay close to the valley floors will preserve and buffer developmental pathways in the face of evolutionary change.

For the analyses of risk factors for disease due to recently acquired infection and for transmissibility, we classified links with 6 10 SNPs different as uncertain unless the mutation rate was <0.003 SNPs/day, to allow for larger changes over long time periods.

These are large changes, tracked over decades, but often the difference between death and life depends upon the difference between two o'clock and four o'clock — upon tiny infrastructural adjustments and barely perceptible shifts in situation.

The similar proportion in spending in 2005 potentially suggests that the malaria burden at MMH may have been higher to begin with, thereby explaining the larger change over time in resources devoted to malaria admissions compared with LGH.