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On aggregate level, there was a moderate to large association between impairment and disability (pooled ES z) = 0.69; 95% CI, 0.66 – 0.66).
The large association between viability in different environments we observed should arise if genotypes viable in different environments require nearly identical super-essential reactions.
Strong evidence of a large association between absolute magnitude of effect size and explicit reporting of 'no funding' suggests authors of unfunded trials are likely to report larger effect sizes, notwithstanding direction.
While no associations were found between effect size and IF, reporting sources of funding, or conflicts of interest, there was strong evidence of a large association between absolute magnitude of effect size and the explicit reporting of 'no funding'.
Regression analysis (Table 2) showed strong evidence of a large association between the CDF and increased prescribing in England compared with Wales for both drugs (lapatinib PVR 7.44 (95% CI 5.81 9.54), P<0.001, panitumumab PVR 5.40 (95% CI 1.20 24.42), P=0.03).
Regression analyses (Table 2) showed correspondingly strong evidence of a large association between the introduction of the CDF and increased prescribing in England compared with Wales for bevacizumab (PVR=3.28 (95% CI 2.59 4.14), P<0.001), but only marginal evidence of a modest association for sorafenib (PVR=1.29 (95% CI 1.00 1.67), P=0.05).
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Based on the current sample size, at an alpha level of.05, the four-predictor regression model had an 80percentnt likelihood of capturing 'moderate to large' associations between each of the four predictors and the dependent variable [ 33].
Alternatively, some prior studies reporting large associations between lithium treatment and reduced suicide risk may have been biased by inadequately controlled initial confounding or differences in selection occurring during treatment [ 10, 11].
Similarly, the largest association between intervention and HIV risk was with STIs treated.
We found a larger association between inflammatory arthritis and CVD ORR = 1.5) than between diabetes mellitus and CVD ORR = 1.3).
Partial correlation coefficients were calculated and regression analysis carried out for the time lag (interval) over which the largest association between these variables was identified.
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