Sentence examples for large and defined from inspiring English sources

The subtle mammalian increase in variability is fundamentally different to the large and defined 90° re-orientation in Drosophila neuroblasts (Knoblich, 2008; Siller and Doe, 2009).

Colorectal cancer metastatic to the liver is particularly suited to validate novel markers, since the condition is characterised by a large and defined tumour burden.

By use of a large and defined phosphopeptide library containing numerous sequence inversions and structural isomers, tryptic in nature, we have investigated a key challenge in mass spectrometry-based proteomics, that of peptide isomers.

The next step is to study the clinical relevance and utility of our approach to the detection of CTCs, by analysing samples from a large and defined patient cohort.

Importantly, the switch of APs from symmetric proliferative to asymmetric neurogenic divisions occurs mostly without large and defined re-orientations of the spindle, but with only subtle deviations (Huttner and Brand, 1997; Haydar et al., 2003; Kosodo et al., 2004; Konno et al., 2008; Shitamukai et al., 2011).

Although the combination of digital colposcopy imaging with the communication infrastructure of the web would greatly facilitate the implementation of mid/large scale programmes, there have been very few examples of intercolposcopist agreement study with large and defined geographical basis [ 28].

Defining the precise extent of the critical region of the Men locus awaits examination of a much larger and defined set of rearrangements.

It was also significant to recognize distribution of the studied receptors within myoma, since it has been suggested that the size of a myoma affects distribution of protein expression and, therefore, we examined expression of selected receptors in small and large myomas and defined the effect of female age on the expression level of the receptors.

A total of 294 QTL (all considered to be of large-effect and defined as 1-Mb windows of the genome explaining ≥ 1% of additive genetic variance) were identified across twelve traits recorded in ten breeds (Table  2).

These chemical elements are called "basic," or "principal," because they are introduced into aluminum alloys in large amounts and define their microstructure and properties.

Regarding properties, they have to be available in large quantities and define qualities with low impurity contents.