Sentence examples for large amount of variants from inspiring English sources

Variant calling usually yields a large amount of variants, even when restricting the calling to only output variants with a minimum quality and probability not to be a sequencing artifact.

This separation of effects among the strains could mean a relatively small number of variants explaining a relatively large amount of variance and motivates future mapping studies.

In this work we aim to take a step ahead in the development of the discipline by introducing a large amount of BFOA variants resulting from the combination of some advanced design decisions applied on Dasgupta et al.'s self-adaptive version.

Among the large amount of novel variants detected by targeted resequencing, we selected 200 SNPs for further association study in a population consisting of 2634 cows.

However, it is challenging to distinguish true cancer-associated mutations from a large amount of "passenger" variants detected in these studies that are likely to be irrelevant to cancer progression.

Despite the high allelic heterogeneity and the large amount of novel ABCA4 variants detected in this screening, the p.Arg1129Leu mutation was found to be the most frequent disease-associated allele (5/62; 8%).

Currently, demonstrating an actual effect on gene function of such variants is limited, but will be of importance as improving sequencing technologies provide larger amounts of variant data.

Motivation: Association tests based on next-generation sequencing data are often under-powered due to the presence of rare variants and large amount of neutral or protective variants.

The large amount of epistatic variance in the cross could be explained by the breakdown of coadapted variant combinations.

Given the large amount of individual variation.

This may suggest that our mismatch filtering protocol eliminates large amounts of false variants, which would not be validated at the SNP design step.