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A high degree of variability is obviously favourable, as freely giving the materials for selection to work on; not that mere individual differences are not amply sufficient, with extreme care, to allow of the accumulation of a large amount of modification in almost any desired direction.
Darwin described this explicitly in the Origin (Darwin 1859, p.40 41): A high degree of variability is obviously favourable, as freely giving the materials for selection to work on; not that mere individual differences are not amply sufficient, with extreme care, to allow of the accumulation of a large amount of modification in almost any desired direction.
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Remarkably, a large amount of polymorphism and structure modifications, indicating intrapopulational polymorphism with not all accessions having an identical genomic structure, was observed using GISH [ 6, 19, 20] and C-banding [ 22- 24] techniques.
However, simple models are created, which is mainly due to exercise using CAD software with limited modeling capability, or requiring large amount of time for modeling and modification.
Thinopyrum intermedium is a species possessing a large amount of cytogenetic polymorphism and structural modifications of chromosomes, with not all accessions previously studied having identical genomic structure [ 20, 22- 24].
However, repeated modifications and a large amount of experimental data are necessary for the parameter identification.
An ultimate secondary battery of sixteen 5 /38 in dual mounts, sixteen Bofors 40 mm in quadruple mounts and eight single Oerlikon 20 mm was called for by the board in 1941, although they were not certain the ships could handle the added weight and it would take a large amount of time in dry dock for these modifications to take place.
Spacers have been developed through empirical modifications, so that a large amount of test data are required for optimum design of the spacer.
In agreement with this, an increasingly large amount of experimental data shows the relevance of chromatin modifications in development [ 5], disease [ 6], etc.
Due to mechanical harvesting large amount of straw is left in the field which implicates modification throughout the agriculture environment.
As shown for Distalless, introns in the "regulation of transcription" GO category often had a large amount of CG methylation in addition to the non-CG modifications.
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