Despite being recognised as a key determinant of glucose yield, many aspects of this trait, and specifically how the trait differs between genotypes to result in such large alterations to glucose release yields, remains a mystery.
These additional variation types are very likely harmful due to large alterations to genes and coded proteins.
These biological effects are mediated by large alterations to gene expression through a highly conserved signal transduction pathway [ 3– 6].
No one knows exactly how higher average temperatures will translate into, say, changes in precipitation, but, considering that there are more than six billion people on the planet, it wouldn't take a very large alteration to create very significant problems.
At smaller scales, engineering works may cause large local alterations to the local processes that control the morphodynamics of intertidal areas and understanding the dynamics of such areas is of prime importance for their use and management.
Chromosomal abnormalities, that is to say large scale alterations to the DNA, be they deletions, duplications or translocations, can have more severe effects.
We studied daily survival rate [DSR] of greater sage-grouse (Centrocercus urophasianus) from 2008 to 2010 in an area in Wyoming experiencing large-scale alterations to the landscape.
On Monday, a local journalist and blogger, Andrey Konoval, documented the alterations to the large portrait of Mr. Volkov in a post on his blog, illustrated with before and after pictures and two brief video clips, showing the revised version of the billboard, and the blogger's unsuccessful attempt to peel the sticker off.
While no new locales were introduced in Episode One, large alterations were made to the appearance of both City 17 where the game takes place and the Citadel from the end of Half-Life 2 to reflect the changing shape of the world and remind the player that their actions have major effects on the story line.
It is possible that the entorhinal cortex is driven by resetting because it may be more computationally demanding to make large alterations in the representation of the distance than to make small changes.
