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Three of the altered peptides result in large alterations in the interface: the Y8A variant removes a bulky tyrosine side chain, the V7R variant replaces a hydrophobic valine residue with a large positively charged arginine residue, and the Y5K-IBA variant replaces the central tyrosine residue with a bulkier and more flexible hapten.
Nonetheless, large alterations are needed to achieve low BER values.
Degeneration and injuries of the intervertebral disc (IVD) result in large alterations in biomechanical behaviors.
All the highly quantized DCT frequencies (whose quantization coefficients are greater of a threshold ) are discarded during the embedding because small changes in these coefficients result in large alterations in the respective dequantized coefficients.
And some periods do produce unusually large alterations in constitutional principles; Franklin Delano Roosevelt's New Deal, which involved no formal amendment, is the most obvious example.
While no new locales were introduced in Episode One, large alterations were made to the appearance of both City 17 where the game takes place and the Citadel from the end of Half-Life 2 to reflect the changing shape of the world and remind the player that their actions have major effects on the story line.
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No one knows exactly how higher average temperatures will translate into, say, changes in precipitation, but, considering that there are more than six billion people on the planet, it wouldn't take a very large alteration to create very significant problems.
The ammonia pressure in tank B showed a large alteration after the second measurement.
One can see that the change in hardness is comparatively small for BH3 adsorption (Δŋ = −0.031 eV) whereas meaningfully large alteration is observed for BF3 adsorption (Δŋ = −0.156).
The dietary comparison revealed large alteration in gene expression in all the tissues studied between fish on the two diets.
The proportion of large genetic alterations that followed repair of irradiation-induced damage might be higher than that observed in this study because a large alteration affecting an essential gene might not be transmitted to the M2 generation [ 39].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com