This allowed us to obtain fairly coherent sets of reliable orthologs forming well-defined groups that are of adequate size (the largest containing only 297 sequences) and biologically relevant.
However, more research is needed into the effectiveness of such programs with a large sample size, adequate methodological and statistical analyses and an extended follow-up.
Nevertheless, because the results of numerical simulations are affected by the statistical characteristics of the concerned landslide dataset, it is hard to find universally applicable criteria for adequate (large enough) sample size.
In order to overcome limitations, future researchers are advised to use standardized and objective measurements of sleep, follow-up or longitudinal designs, representative population samples, large sample sizes, adequate comparison groups, as well as comparison groups with other trauma experiences.
While randomized control trials are the preferred design for impact evaluation, they require relatively large sample sizes, adequate control groups, and exposure to a well-defined primarily biomedical intervention [ 43, 57].
The deviations from the model at points further up the column indicates that the coalescence mechanism described by the model is not adequate for large bubble size distributions which behave differently from small bubble size distributions.
Strengths of our study include a population-based design, large sample size with adequate power to detect main gene effect and gene-smoking interaction effect, integrative analysis with gene expression data, and a systematic approach in evaluating the joint effects of multiple SNPs.
The large sample size provided adequate power to explore statistical associations of interest and to explore confounding and effect modification.
The Millennium Cohort consists of members from all branches and components of the Armed Forces, yielding a large sample size with adequate power to detect meaningful differences among subgroups of the population.
The rationale of ICCC is to address the specific objectives based on the hypotheses set out below by creating a CAP cohort with large sample size with adequate power.
The design of the RCT incorporates a large sample size with adequate power to detect the primary outcomes, and a long follow-up period to observe meaningful improvements in patient health outcomes [ 18, 19].
