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The lap function on the iPhone's stopwatch turns out to be handy for timing contractions.
Since RGD peptides or anti-CD47 IgG did not modify the biological activity of LAP, we presume that the inhibition of LAP function by clone A6.1 was not due to blocking CD47 or RGD peptide binding regions.
This is based on the fact that the anti-TSP-1 antibody used to inhibit LAP function in these studies was the clone A6.1, which targets the C-terminal collagen type V binding region of TSP-1.
To control distance and determine speed, participants wore a Forerunner with the lap function set to 1-km.
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Because of the multiplicity of immunologic processes in which TGF-β1 plays a role, we hypothesized that LAP could function independently to modulate immune responses.
The Forerunner was set on lap speed function (400 m laps) as we have previously found this most appropriate for maintaining speed [ 10].
In these allegations the act was apparently performed with the pig's head resting on a colleague's lap, and functioned as a means of entry into the notorious Piers Gaveston society, supposedly posher than Bullingdon (although friends deny Cameron was ever a member of the Piers Gaveston society).
We report that surface-immobilised LAP, which functions exclusively as an αvβ6-dependent ligand in keratinocyte-derived cells, promotes adhesion, migration and increased pro-MMP-9 secretion.
Currently, LAP is presumed to function only as a sequestering agent for active TGF-β1.
Recently, a genetic abnormality affecting the function of LAP was described as the underlying cause of a naturally occurring human disease called Camurati-Engelmann's disease (CED).
AM5 activates PRA, but suppresses plasma aldosterone, maintains natriuretic peptide concentrations despite falls in LAP and enhances renal function.
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