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A subset of probes, called landmarks, was selected based on their full expression profiles within the compendium.
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Landmarks are selected to participate either as active or passive.
Sufficient landmarks are selected in I c along with their peers in I d.
Through several phases, highly distinctive landmarks are selected, e.g., mutual consistency checks ensure the quality of the landmark.
The landmarks were selected to maximise variation among individuals.
Two landmarks were selected for this test: a difficult-to-visualize landmark (LM2) and a conspicuous landmark (LM6).
Landmarks were selected to represent clearly homologous points, such as suture junctions or extreme points of curvature, and to fully sample the morphology of the entire skull.
A set of homologous landmarks [ 27] was selected to best capture shape variation in each species (additional file 1).
The linear affine transformation (in combination with a subsequent landmark-guided manual registration) was selected over non-linear transform methods to minimize loss of signal due to warping, which is relatively greater in the small subcortical regions [68] relevant to our a priori hypotheses.
A landmark time of 4 months was selected as the majority of EPP procedures were performed within the first 4 months.
Before the study sample was selected, the anatomical landmarks described in Table 1 were marked on the skulls with a pencil by means of consensus of two observers (JD and ZF).
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