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The principle is simple: expensive landmark studies are harder to brush under the carpet, but small ones can disappear more easily.
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But no sooner had these landmark studies been completed than Lipitor emerged as a rival.
Two landmark studies were published that evaluated the impact of shorter duration of antibiotic therapy in ventilator-associated pneumonia (VAP) [15, 16].
Smith's claim that the EPA air-quality rules are justified solely on these two landmark studies is false.
Therefore, these landmark studies were less likely to be identified by the search "anesthesia".
However, the struggle to repeat, improve and standardize the results of the initial landmark studies is ongoing.
Although these landmark studies were followed by several others, the number of oncogenes discovered in this way remained rather limited.
Two landmark studies were published that evaluated the impact of shorter duration of antibiotic therapy in ventilator-associated pneumonia (VAP) [ 15, 16].
These landmark studies were followed by measurements of CSF flow in healthy controls, undertaken by numerous groups and focusing mostly on aqueductal flow and demonstrating reliable measurements [ 44, 45, 49, 51, 156, 157].
In 2014, a landmark study was published demonstrating that the expression of androgen receptor splice variant (AR-V) 7 was a negative predictive biomarker for response to abiraterone acetate and enzalutamide in metastatic castration-resistant prostate cancer (mCRPC) patients.
After the results of that landmark study were reported in 1993, SMBG was considered the standard of care for type 1 diabetic patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com