Since the RDL-antiserum does not yield strong immunolabeling we cannot confirm the Gal4 expression pattern in the lamina as representing RDL protein expression.
Expression of the basal lamina protein laminin was also observed.
TLR9 protein expression was mainly in the lamina propria infiltrate.
Hence, in this study we examined the protein expression levels of a nuclear lamina component, lamin A/C, and three LINC complex components, SUN1, SUN2, and nesprin-2 in breast cancer tissue.
Abnormal splicing of the LMNA gene, which encodes nuclear lamina protein lamin A, or prelamin A, results in the expression of a truncated lamin A protein called progerin, which leads to Hutchinson Gilford progeria syndrome [ 20, 21].
Lamina propria (LP) DC showed higher levels of TLR 2, 3, 4 and 9 protein expression than spleen and MLN DC, with most TLR-expressing DC in the gut being CD11clo, class II MHClo, CD103–, CD11b– and F4/80–.
We observed CagA protein expression in tumor cells of the gastric mucosa, submucosa and lamina propria, as well as scattered expression in the adjacent tumor-free gastric mucosa of H. pylori-positive gastric MALT lymphoma patients.
Intranasal administration of mRNA-loaded nanomicelles provided an efficient and sustained protein expression for nearly two days in nasal tissues, particularly in the lamina propria which contains olfactory nerve fibers, with effectively regulating the immunogenicity of mRNA.
The spinal Fos protein expression study demonstrated that the optimal EA selectively suppressed Fos expression in superficial laminae (I/II) and activated it in deeper laminae (III/IV) of the spinal dorsal horn.
This switch in cytoskeletal protein expression from epithelial cytokeratin to mesenchymal vimentin is most probably induced by the lack of a basal lamina, crucial for the formation of tissue-specific form and function [ 32] and epithelial polarization [ 10, 32, 33].
