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The test set (n = 18) consisted of BSPM data from patients who underwent a balloon-inflation angioplasty of either the left anterior descending coronary artery (LAD) (n = 7), left circumflex coronary artery (LCx) (n = 2), or the right coronary artery (RCA) (n = 9).
Study design: CF cases identified from the CF Foundation National Patient Registry and diagnosed between 1982 and 1990 were categorized as: early asymptomatic diagnosis (EAD; n = 157), early symptomatic diagnosis (ESD; n = 227), later asymptomatic diagnosis (LAD; n = 161), and later symptomatic diagnosis (LSD; n = 3080).
Sham animals underwent thoracotomy without permanent LAD (n = 6).
Briefly, male Sprague Dawley rats (200 to 250 g) underwent permanent left anterior descending artery ligation (LAD) (n = 6) as previously described [2],[2]].
MI was induced in 10- to 12-week old male Swiss mice by ligation of the left anterior descending coronary artery (LAD) (n = 7), as previously described [26].
Landrace pigs were subjected to a transient occlusion of the proximal left circumflex artery (LCx) (n = 6) or mid-left anterior descending artery (LAD) (n = 6) for 150 min.
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Control rats (n = 13) underwent LAD ligation and rethoracotomy without therapy, and five rats underwent a sham operation in both surgeries.
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