Exchange reactions would cause the specific activity of brain lactate (i.e. the quantity of label in lactate divided by the quantity of unlabelled lactate) to fall due to dilution of labelled brain lactate by unlabelled blood lactate.
The non-oxidative breakdown of glucose to pyruvate or lactate, i.e. glycolysis, is commonly increased in the post-ischemic heart [ 37– 37].
As such, estimating the SIG from the AG, after correcting for albumin and PO4, and after subtracting lactate (i.e. AGc), may be a reasonable substitute for the long hand calculation [ 7, 39, 46].
From this point onwards, MAP was maintained at 35±5 mmHg for a period of 90 minutes, either by further withdrawal of blood during the compensation phase or by administration of Ringer's lactate i.v. during the decompensation phase.
Both groups were treated with HH (30 ml/kg of Ringer lactate i.v., in 20 minutes) in the early (E30 minute) and late (L6 hour) phases of sepsis.
We included studies that met the following inclusion criteria: ED or ICU setting; disparities due to race, language, gender, socioeconomic status, insurance status or geography; process of care measures (antibiotics, lactate, i.v. fluid resuscitation, central line placement, vasopressor use) or outcome measures (mortality, length of stay, complications, costs).
Blood gas analysis (pH, pO2, pCO2; i-STAT, Heska, East Windsor, NJ, USA), (Additional file 3: Figure E4), laboratory data (ACT, sodium, potassium, blood urea nitrogen (BUN), glucose, lactate; i-STAT, Heska, East Windsor, NJ, USA), and a hematocrit (Stat Spin MP, Iris Sample Processing, Westwood, MA, USA) were measured immediately after blood sampling.
The limits of detection were 0.07 ng/ml for PCT (Kriptor; Brahms, France), 4 mg/L for CRP (turbidimetric method; Diagam, France) and 1.25 mmol/L for lactate (i-STAT; Abbott, USA).
A phase I trial was conducted with lobaplatin (D-19466; 1,2-diamminomethyl-cyclobutane-platinum (II -lactate) II -lactatedaily for 5 days every 4 weeks.v.
The objective of this prospective observational cohort study is to determine the predictive value of D-lactate, I-FABP and other more common serological markers of ischemia (L-lactate, lactate dehydrogenase (LDH), creatine kinase (CK) and alanine aminotransferase (ALAT)) in intensive care patients suspected to have intestinal ischemia.
To discover the reasoning behind why anyone would make a toy that allows children to mock-lactate, I called up Berjuan Toys, the makers of the doll, and talked to an anonymous spokesman.
