That should help to deflect the environmentalists' charge that the WTO is secretive and lacks know-how.Changing the WTO's rules, however, is a taller order.
E. muris can induce inflammation in mice, but it appears that E. muris lacks known TLR and NLR ligands, with the exception, perhaps, of bacterial nucleic acids.
While Krit1 and OSM proteins both have known structural domains and functionally link to several important signaling pathways, including integrin signaling, the p38 MAP kinase pathway, and RhoA-rho kinase regulation, PDCD10 lacks known structural domains.
ER lacks known functional motifs that would allow for nongenomic mechanisms of estrogen action [ 27].
dOrphan, protein that lacks known homologs and does not contain any Pfam domains.
This cytosolic tail lacks known signaling motifs such as phosphorylation sites or kinase domains.
Conventional hormonal or anti-HER2 targeted therapies have no favorable value for TNBC which lacks known common therapeutic targets.
WFS1 encodes a 100 kDa integral membrane protein of the ER that lacks known catalytic domains (Hofmann, 2003).
Both SNPs map to a single linkage disequilibrium block spanning ~60 kb in a region on chromosome 6q23 that lacks known genes or transcripts.
Btg3, which is a member of the family that lacks known representative in avian species, is also expressed in the mouse interdigits.
Additionally, this also means that our approach currently cannot be used to rank novel candidate OD genes if an OD lacks known causal genes.
