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This, in our belief, relates to the high purity grade of our alginate that lacks interfering substances, such as proteins or endotoxins that may negatively affect the equilibrium by raising negative charges or altering the three-dimensional hydrogel architecture [ 29].
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The practice of pulling loose loops of cord over the baby's head also lacks evidence and may interfere with the normal physiology of birth and risks avulsion and subsequent neonatal bleeding [ 28].
Induced expression of a constitutively active RB that lacks nine phosphorylate sites PSM-RBB) interfered with doxorubicin-induced activation of caspase-3 as a consequence of G1-arrest [14], [15].
As a consequence, our antibody lacks an ability to appreciably interfere with FGF19 signaling or phosphate homeostasis.
Previous reports showed in vitro that H141A HDAC-1 lacks deacetylase activity and can interfere with the function of endogenous HDAC-1 in myoblast cells (Hassig et al., 1998; Mal et al., 2001; Ito et al., 2002).
As observed previously, oligonucleotide M4, which is complementary to positions -4 to -23 upstream of the Bcl-xL donor site but lacks a tail, did not interfere significantly with Bcl-x splicing at any of the concentrations tested (Fig. 1C and 1D).
"One of his biggest problems was that a lack of sleep was interfering tremendously with his work and going to school," Ms. Daly said.
CsH lacks immunosuppressive activity and only weakly interferes with the multidrug-resistance protein P-glycoprotein (MDR1).
They show that the truncated protein lacks endogenous function yet does not interfere with other coexpressed Zic proteins.
Expression of β4 integrin that lacks the hemidesmosome targeting domain interferes with tissue polarity and NFκB activation and permits apoptosis.
In Figure 6a, we summarize the results from these deletions and others, indicating that only mutations interfering with the GH3 domain lacked the ability to bind to MFN2.
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