It is, thus, especially useful if one deals with 'fuzzy' constructs that lack consensual definitions.
With the exception of Takayasu arteritis (TAK), Kawasaki disease, polyarteritis nodosa (PAN) and Behçet disease [ 9– 11], we lack consensual and widely validated diagnostic criteria for most of the vasculitides.
Once again, Fifty Shades is NOT about BDSM because it lacks the consensual context in which BDSM is predicated.
It is not perfect, partly because some issues in experimental design lack consensual answers regarding their impact on quality and partly because choices need to be made regarding what issues are most important to address.
As mentioned above, the neural mechanisms underlying habituation remain poorly understood, and this uncertainty helps to explain why the abnormal habituation pattern in migraine still lacks a definitive consensual interpretation [93 95].
Lacking these conditions, consensual exchange cannot occur, and rational individuals will try to cheat others to maximize their gain.
Although lacking a classical consensual transmembrane sequence, Hsp70, the major stress-inducible member of the HSP70 family, has also been found to be present on the plasma membrane [3], [4], [19] and in the extracellular milieu of cells with an intact membrane [20] [22].
This heterogeneity is mainly explained by the lack of consensual definition [17, 21] and by the variability in VAP bundles implementation rates [22, 23] in the different ICUs.
The lack of consensual protocols and clinical guidelines can lead to deficiencies in the attention to these patients and to inadequate use of resources.
The exact prevalence of the disease varies according to the study design and its estimate remains difficult mainly because of the lack of consensual diagnostic tools easily usable in population studies.
