Genes lacking homologs in related genomes also lacked uptake sequences, strengthening the evidence that uptake sequences do not drive lateral gene transfer between distant relatives but instead accumulate after genes have been transferred.
We noted that the scans lacking differential uptake typically also demonstrated a predominance of early FDG distribution into non-uterine, caudal structures such as the tail or left hindquarter (Fig. S3).
Alternately, in R. leguminosarum, braC mutants are effective in alanine uptake (but are lacking in the uptake of the other three amino acids) [ 38].
Because this lacks the uptake system for As III), it is resistant to the metalloid.
In addition, the bone density of smokers may be low because smokers lack calcium uptake or tend to exercise less than never smokers [ 36].
In particular, the experiments with digitonin-permeabilized cells revealed that the UCP3R167G mutant exhibits almost normal function at high Ca2+ concentration but lacks Ca2+ uptake activity under low Ca2+ conditions.
The I524K/E/Q mutants expressed well and localized correctly despite lacking any glutathione uptake capability.
HeLa cells were chosen as an established model known to exhibit efficient glucose uptake and lacking endogenous expression of GCKR and GCK [ 7, 23].
In macrophages lacking DGAT1, the reduced uptake of modified lipoproteins and the increased efflux of cholesterol result in markedly reduced foam cell formation.
Lack of uptake was associated with a lack of understanding of the immediacy of the effect of detrimental behaviours, especially sugar ingestion and an emphasis on instant self-gratification.
