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Downregulation in HCC could be responsible for a worse or lacking response towards platin treatment.
Recently, we have reported that HNSCC cells lacking response to radiotherapy are characterised by increased expression of Rac1 protein (Skvortsov et al, 2011).
The cardiodepressant IL-1β effect was documented by a lacking response in pulsation amplitude to the isoproterenol-challenge (control: n = 20, 148% ± 20 versus IL-1β : n = 27, 103% ± 3*, P < 0.05), which was preserved by co-incubation with Dex.
Interestingly, combining the data from primary breast cancer [ 15] and the metastatic samples analyzed in this study, we find 5 out of 24 tumors lacking response to anthracycline or mitomycin therapy to harbor RB1 point mutations or indels contrasting 1 out of 67 with response (P = 0.004).
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The orco mutants completely lacked responses to 9-tricosene.
Our research is in agreement with previous researches which revealed the lack response of this variety to NPK fertilizer.
Drosophila mutants devoid of the LUSH OBP have defects in avoiding high alcohol concentrations [21] and lack response to a pheromone [22].
At first they blamed the Democrats' lack of response on Harry Reid's desire to deny Republicans a victory.
BLISSFUL LADY saved ground chasing the pace throughout and lacked a response in the lane.
CAUSE WHY reserved from the inside, saved ground throughout and lacked needed response.
I ADORE YOU chased five wide, angled to the inside on the turn and lacked a response in the drive.
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CEO of Professional Science Editing for Scientists @ prosciediting.com