Compared with the study patients, those who could not be included because they lacked repeated CD4 testing were slightly more often women (66%, P = 0.06), older (37, IQR 32 42 years, P<0.001), and intravenous drug users (29% vs 18%, P<0.001).
Whereas FLNa lacking repeat 3 did not co-immunoprecipitate R-Ras (Fig. 1C), confirming that this is the site of association.
In M2 melanoma cells active R-Ras co-localized with FLNa but did not co-localize with FLNa lacking repeat 3. Thus, activated R-Ras binds repeat 3 of FLNa.
Only deletion products lacking repeat A in combination with one or more of the other repeats show impaired localization.
Replacement of one U6 promoter with an H1 promoter would produce a siRNA expression cassette lacking repeat sequences.
This mutation apparently contributes to differences in the expression of certain spliced mRNAs encoding NOD1 protein isoforms lacking repeats within the LRR domain.
Similar to the q-PCR results with CLDN16, constructs containing XIST lacking repeat A, or no XIST (vector sequences only) showed no change in allelic ratio upon DOX induction; however, in these cell lines the DNA ratio showed an equivalent allelic DNA ratio, reflecting karyotypic instability of the HT1080 line.
Total pregnancy weight gain has been associated with infant birthweight; however, most prior studies lacked repeat ultrasound measurements.
Our results support this idea, because patients with primary insomnia and normal glucose tolerance had similar total sleep times compared to OSAS and RLS patients, but lacked the repeated arousals induced by apneas or PLMS.
LAVA elements, however, lack such repeated internal arrays.
