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There are many reasons why novel therapeutics fail in clinical trials but these failures are often attributed to lacking quality of preclinical data.
The evidence base is insufficient when scientific evidence is lacking, quality of available studies is poor or studies of similar quality are contradictory.
Four data sets had to be excluded due to lacking quality of the recorded EEGs: In two cases, the raw data contained more than twenty percent of segments with artefacts; another two recordings had no impedance information and were excluded for this reason.
Similar(57)
for instance: ~ Not giving others credit and opportunity allow small success but severely limits your own leadership and growth -- lacking qualities of accepting others contributions with thankfulness.
Withholding antibiotics for a pneumonia in someone who lacks quality of life is not the same thing as deciding not to replace a broken hip.
"To suggest that nurseries are lacking quality in terms of early-years education is unfair.
"We lacked energy, we lacked quality, one of our poorest displays of the season.
Firstly, the routine program data may lack quality because of poor documentation.
But we lacked the quality-of-life amenities that separate good cities from great cities.
But they lack the quality of real democracy.
But it lacked the quality of social connectedness that marks JR's best work.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com