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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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lacking of dose-response

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "lacking of dose-response" is not correct in written English.
The correct expression would be "lack of dose-response." Example: "The study showed a lack of dose-response relationship, indicating that the drug's effectiveness did not increase with higher doses."

⚠ May contain grammatical issues

Science

Human-verified examples from authoritative sources

Exact Expressions

1 human-written examples

However, it is still lacking of dose-response relationship of SND in cardiovascular disease at the metabolic level.

Human-verified similar examples from authoritative sources

Similar Expressions

59 human-written examples

A more likely reason is the lack of dose-response relationship for DNA strand breaks and the high interanimal variation.

The lack of dose-response relationship may indicate a maximal rate of particle-induced DNA strand breaks was achieved at the studied doses.

Because of the lack of dose-response information and reliable estimates of future regional climates, however, it takes a historical perspective.

Given the lack of dose-response data for human neurotoxicity, the risk assessment was based on rodent studies and supported by primate studies of acrylamide neuropathy.

There is also no association between histamine-2 receptor antagonists and the risk of HCAP (adjusted OR=0.95, 95% CI 0.75 to 1.21), suggesting a lack of dose-response relationship between potency of gastric acid suppression and the risk of HCAP.

Science

Gut

Only 15% of the chemicals reviewed (i.e. 13/85) were found to have a dose-response threshold and the remaining 26% (i.e. 22/85) were categorized as 'unknown' due to a lack of dose-response information.

The lack of dose-response reported by Thomas et al was possibly due to selection bias, with subjects highly exposed to vibration (enough to have vibration white finger syndrome) [ 40].

Based on the observed toxicity, the lack of dose-response relationship and the immunomodulatory effects seen at relatively low-dose IL-2, the recommended dose for a phase II study is 3 x 10 6) IU day-1 using the present treatment schedule.

None of these significant differences were considered to be toxicologically relevant due to a lack of dose-response relationship, relatively low magnitude of change, absence of occurrence in both sexes, and/or the lack of important changes in related clinical parameters.

Hierarchical testing showed no significance, indicating a lack of dose response across the 3 mesalamine doses.

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Expert writing Tips

Best practice

Always use the correct phrase "lack of dose-response" or "absence of dose-response" for clear and professional communication in scientific and medical contexts.

Common error

Avoid using "lacking of" as it is grammatically incorrect. Use "lack of" instead. For example, it is more appropriate to say, "There is a lack of evidence" rather than "There is lacking of evidence".

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

85%

Authority and reliability

3.8/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "lacking of dose-response" attempts to describe the absence of a relationship between the dose of a substance and the resulting response. However, as noted by Ludwig AI, the correct phrasing is "lack of dose-response".

Expression frequency: Rare

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Encyclopedias

0%

Ludwig's WRAP-UP

In summary, while the phrase "lacking of dose-response" may appear in some contexts, it is considered grammatically incorrect. The correct and preferred phrasing is "lack of dose-response" or "absence of dose-response". Ludwig AI indicates that the intended meaning involves describing a situation where there is no expected relationship between a dose and its effect, primarily within scientific and medical contexts. It's crucial to use accurate language, focusing on the more standard terms such as "lack of dose-response relationship" to ensure clear and professional communication.

FAQs

How do I correctly use the phrase "lack of dose-response" in a sentence?

Use "lack of dose-response" to indicate that there is no proportional relationship between the amount of a substance administered and the effect observed. For instance, "The study revealed a lack of dose-response, suggesting the treatment's effectiveness plateaus at lower doses."

What is the difference between "lack of dose-response" and "absence of dose-response"?

While "absence of dose-response" and "lack of dose-response" are largely interchangeable, "absence" might imply a complete and total absence, while "lack" could suggest a deficiency or inadequacy. The choice often depends on the specific context and desired emphasis.

What are some alternative phrases for "lack of dose-response"?

Depending on the context, you could use phrases such as "no dose-response effect", "dose-response relationship not evident", or "dose-independent response".

Why is "lacking of dose-response" considered grammatically incorrect?

The correct phrasing is "lack of dose-response." The construction "lacking of" is generally non-standard. It is more appropriate to use "lack of" to express the absence of something.

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Source & Trust

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Authority and reliability

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Real-world application tested

Most frequent sentences: