Sentence examples for lacking efficacy from inspiring English sources

The lacking efficacy of GW0742 is in contrast to previous studies in polymicrobial sepsis [2, 7], which, however, report data from young and otherwise healthy rodents.

Therefore, we cannot exclude that sepsis further aggravated PPAR-β/δ down-regulation and thus contributed to the lacking efficacy of GW0742.

All relevant information regarding defective health products was compiled and exclusion criteria were as follows: veterinary medicines; medicines lacking efficacy or acquiring general safety issues; herbal and probiotic products; dietary and cosmetic products; and other natural heath product recalled for regulatory reason (ie, those do not have a valid marketing authorisation).

In this context, the role of EP is still not well defined: despite the unanimous data from (mostly unresuscitated) rodent models, the findings in clinically more relevant, resuscitated large animal models are controversial - both beneficial effects [ 14- 16] and lacking efficacy [ 17, 18] were reported.

The resulting alerts and recalls were compiled and exclusion criteria included the following: drug alert replaced by another updated one, drug alert duplication, alert about clarification of medicine information, medical device alert and alert about medicines lacking efficacy or having significant toxicity.

As monotherapy, however, anti-angiogenic treatment lacked efficacy in randomized clinical studies so far.

Unfortunately, available therapies lack efficacy in preventing progression to its end stage phase.

Both infliximab and adalimumab have been shown to be effective in Crohn's disease while etanercept lacks efficacy in this disease.

Conclusion: Under the conditions of this trial, chlorhexidine vaginal irrigation lacked efficacy in the prevention of clinically diagnosed maternal and neonatal infectious morbidity.

GRK2 lacked efficacy at both endothelin and alpha(1 -adrenergic receptors despite massive overexpression.

However, we currently lack efficacy and safety data for longer dexmedetomidine infusions.