Sentence examples for lack of trial data from inspiring English sources

Critics grumbled that many Sugar Busters! recipes were high in both fat and calories, and decried the lack of trial data that might prove the diet's effectiveness.

It would be entirely inappropriate to use the findings of this review to deny patients with cancer access to treatment for depression and depressive symptoms because of a lack of trial data on effectiveness.

Bevacizumab is an inhibitor of vascular endothelial growth factor widely used as an "off-label" treatment of neovascular age-related macular degeneration (AMD), despite the lack of clinical trial data on efficacy or safety of this drug.

Because of the rarity of Gaucher disease and the consequent lack of randomized trial data, recommendations are based on evidence from observational studies, case reports and expert opinion.

There is a remarkable lack of randomized trial data on optimal management of coronary artery disease (CAD) in patients with chronic kidney disease (CKD).

There remains a lack of clinical trial data examining the role of tolvaptan, or indeed any other drug, in patients with preserved systolic function presenting with AHFS.

Nevertheless, because of the renal clearance and lack of clinical trial data in subjects with GFR <30 mL·min−1, bisphosphonates carry either a warning or a contraindication in the label for use in patients with GFR <30 35 mL·min−1.

Until recently, however, there has been a lack of clinical trial data specific to the management of patients with acute hypertension and clinicians have had little evidence-based guidance as to the optimal agent for BP control.

NCT00765648, clinicaltrials.gov There has been a lack of clinical trial data specific to the management of patients with acute hypertension in the emergency department (ED) and clinicians have had little evidence-based guidance as to the optimal agent for blood pressure (BP) control.

While the laboratory analytical sensitivity and specificity of these techniques for the detection of pathogen DNA in blood has been evaluated, 12 there remains an acknowledged lack of clinical trial data to define the diagnostic reliability of such tests in patients who develop a systemic inflammatory response due to suspected infection.

In the current model, the use of aggregated level data was forced by the lack of comparative trial data versus tiotropium.