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These results are consistent with the lack of synthesis of endogenous granins in rat PC12 cells infected with recombinant vaccinia viruses [ 46].
This lack of synthesis makes it very difficult for physicians and allied healthcare professionals working with PCa to access, interpret and apply the key research findings to their clinical practice.
It thus seems that the development of radiographic damage during the first years after diagnosis is more a reflection of increased degradation of collagen and enhanced turnover of proteoglycans rather than a lack of synthesis of cartilage collagen.
The long and short 4.1R protein bands were observed for the control cDNA 1' construct, whereas removal of the CMV promoter resulted in a lack of synthesis of both 4.1R proteins.
It is likely that this difference is due to lack of synthesis and/or amplification of pathogen-associated molecular patterns (PAMPs), for example RNA replication intermediates, by the heat-inactivated virus.
To rule out the possibility that the lack of interaction between PiSSK1 and the three allelic variants of PiSLF was due to lack of synthesis of PiSSK1, we performed protein gel blot analysis to examine whether PiSSK1 was produced in yeast cells carrying pGADT7-PiSSK1.
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Similarly, in H9c2 cells, where TIP60 cDNA was ectopically expressed, the p53-Lys acetylation was observed along with lack of NOS3 synthesis and abundant BAX synthesis (Fig 8F; lanes 7 9).
Indeed, amnesic patients exhibit a remarkable want of coherence in their thought processes, suggesting that a lack of temporal synthesis underlies, and may indeed in large part explain, the defect of memory.
However, due to lack of automatic synthesis and optimization tools for these circuits, implementation of secure asynchronous circuits encounters many difficulties.
It is challenging, however, due to lack of information synthesis on the ecology of rare plants, lack of effective approaches for habitat assessment at multiple spatial scales, and lack of spatial data for relevant environmental attributes and scales.
Attempts to establish if high level expression of a different surface protein on the surface of bloodstream form T. brucei could complement for lack of VSG synthesis were unsuccessful.
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