Our lack of SCALE-UP abandoners supports this hypothesis.
The evidence that is available tends to show a lack of scale-up necessary to realise the 70% target.
The report is also critical of the lack of capacity to scale up vaccine production in the UK and of the failure of authorities to release the rapid diagnostic antigen test developed by Ministry of Defence scientists.
High pressure homogenization has enormous advantages, including the possibility of scaling up, lack of organic solvents and the production of small particles diameter with low polydispersity index.
These problems were the result of poor innovation management capacity, variability in domestic markets, lack of capital to scale up technologies, and an institutional culture that lacked innovation as a priority.
The lack of this evidence is a major challenge in the process of scaling up mental health care in Low- and Middle Income Countries [ 4].
The many reasons for this slow pace of events include lack of political will for scale up, inadequate resources, lack of administrative capacities, inadequate number, as well as competent Community Health Officers (CHOs), suboptimal levels of local people's participation and different understanding of the concept of CHPS amongst health sector leadership [ 6].
"The scale argument would be even stronger in a Peugeot tie-up in whatever form versus a GM Europe [tie-up]." "Peugeot has a similar problem, lack of scale in the market".
Although individual cases of successful scale-up, in which widespread take up occurs, have been described, we lack an integrated and practical model of scale-up that may be applicable to a wide range of public health innovations in LMIC.
(KI 6) KIs said that a lack of political interest in scale up was a major barrier (KIs 12, 14); they mentioned that campaigns to massively scale-up ART in low income countries (such as the WHO's "3 by 5" campaign, or the US President's Emergency Plan for AIDS Relief) had helped to generate political interest in large-scale implementation.
However, many open issues can be evidenced regarding the true possibility of scale-up, as well as currently lacking information for process design and economical evaluation.
